How to get started

When starting up whole genome sequencing, several considerations about DNA extraction, library preparation, sequencing and data processing are necessary.

You can find a guideline on how to get started here:

ENGAGE Guideline on how to get started (PDF document, 100 KB)

WHO has prepared a landscape paper that summarizes some of the benefits and challenges inherent in the implementation of WGS. It also provides an evidence base for some of the approaches to be considered in the guidance document. This landscape paper can be found via the following link:

Whole Genome Sequencing for foodborne disease surveillance - landscape paper

WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS) has published a document that addresses the applications of WGS for AMR surveillance, including the benefits and limitations of current WGS technologies. It can be found via the following link:

https://www.who.int/publications/i/item/9789240011007